NFL Week 6: Betting Lines and Predictions for Every Game

All the picks in one place! The BookieSmash team breaks down every NFL game for Week 5, and offers the best bet for each game using our wide array of betting sites. Read on before placing your bets this week!


Cincinnati Bengals at New England Patriots

Best Bet: Over 47

Tom Brady's triumphant return was about as successful as the droves of Patriots bettors hoped for as he looked like he never missed a snap in piling up another 400-yard day. The strength of this Bengals team was supposed to be their defense, but they looked shockingly helpless as they allowed the Cowboys to jump out to a 28-0 lead and have been generally only average this season. Most likely, the Patriots will continue to be able to impose their will in the passing game here, and expect them to run even less than they did in last week's 33-point effort, as LeGarrette Blount managed only about 2 yards per carry. The Bengals will have to throw to keep up, so expect both teams to top the 20-point mark in a fast-paced contest.

Baltimore Ravens at NY Giants

Best Bet: Ravens +3

The Giants have generally looked sloppy and out of sorts for weeks, and they continued that trend Sunday night in a stinker of a performance by the offense. The line is completely inept, and Eli Manning is not the sort of QB who does well when the other team can pin their ears back and pressure him at will due to a lack of running game. Yet, this team is somehow considered to be on par with a Ravens team that, while certainly not great, at least usually looks like a professional team most of the team. We like a Ravens defense that's been solid against the pass to continue to frustrate Manning and cover +3 here.

Carolina Panthers at New Orleans Saints

Best Bet: Saints +3

Drew Brees and the Saints always play much better at home, and they're in a beautiful spot coming off of a bye against a Panthers team on short rest. Carolina's banged up too, with Cam Newton and Jonathan Stewart likely to be less than 100 percent coming back from injuries. The matchup looks pretty good for the Saints too, as they should be able to throw all day against a Panthers secondary that's been among the leakiest in the NFL and gave up a number of long passes to even a pretty poor Bucs passing offense.

Pittsburgh Steelers at Miami Dolphins

Best Bet: Dolphins +7.5

This is a spot where everyone with an outlet to bet at is running to fire the Steelers -7.5. It's not hard to see why. The Steelers once again look like they're fielding an elite offense behind Ben Roethlisberger, Antonio Brown, and Le'Veon Bell, with sidekick Sammie Coates getting in on the fun in the 31-13 romp over the Jets last week. Meanwhile, the Dolphins have failed to cover three consecutive weeks and even before that needed a miracle second-half comeback and a major QB injury just to cover a big number against the Patriots. If Miami can't band together and put up a fight at home in a spot where nobody believes in them, it's probably time to completely write these guys off unless they're getting double digits.

Jacksonville Jaguars at Chicago Bears

Best Bet: Jags +2.5

The Jags played much better in a matchup with the Colts a couple of weeks ago in London and are coming off a bye, so they should be well-rested. Meanwhile, the Bears continue to look injured and ineffective, although WR Cameron Meredith looked pretty good in stepping into a bigger role. It hasn't helped that their most talented player, Alshon Jeffery, has gotten very little going with more than a quarter of the season gone. The Jags do have the defense to stymie this passing game, but they've been vulnerable to the run, where they rank 29th in the league. However, this Bears OL doesn't inspire any confidence as they've been unable to open up many holes for Jordan Howard.

San Francisco 49ers at Buffalo Bills

Best Bet: 49ers +7.5

It's finally time for Colin Kaepernick to stop taking headlines for what he does off the field and start producing on it, as he's going to be starting in place of the atrocious Blaine Gabbert this week. A red-hot Bills team is his reward, but the Bills might still be without star DT Marcell Dareus, who has yet to practice this week. Historically, QBs under coach Chip Kelly have really upped their production, and Kaepernick looks like a perfect fit for his offense on paper. As long as he doesn't come out showing the putrid form he had last year, Kaepernick should be a nice boost to this offense to help keep them within +7.5.

LA Rams at Detroit Lions

Best Bet: Lions -3

Matt Stafford and the Lions delivered for us last week with a big home win against the Eagles, and they get an easier assignment this week when the Rams come to town. The Rams are somehow surviving on offense on a diet of tons of Todd Gurley carries mixed with occasional passes to the most no-name group of receivers in the league, but that does not appear to be a sustainable formula for success. The team has been completely unable to run-block for Todd Gurley, as they're averaging just 3.1 yards per carry, and Stafford will eventually find some holes in this defense to get the job done at home.

Cleveland Browns at Tennessee Titans

Best Bet: Browns +7.5

Yes, it is the Cleveland Browns, the only team in the league that has yet to produce a victory. But, it's really hard to buy this Titans team as being more than a touchdown favorite against anyone in the NFL. The Browns got buried by the Pats last week, but they had to play parts of that game with Charlie Whitehurst at QB, and should get Cody Kessler back this week. Kessler might not be anything to write home about, but he's at least managed to keep the ball out of the other team's hands as he'd thrown only one pick in 81 attempts, and that should be enough to keep this within a score.

Philadelphia Eagles at Washington Redskins

Best Bet: Over 44.5

This line opened with the Redskins as slight favorites, but everyone's piling on the Eagles so far despite the Redskins coming away from Baltimore with a pretty surprising road victory last week. Baltimore simply refused to run the ball against this atrocious, league-worst run defense that's giving up 5.1 yards per carry. That won't be a problem for a Philly team that's seventh in rushing frequency, and they should gash this defense and score some points. That will cause Washington to open things up as well, and we should see both teams on the board plenty here.

Kansas City Chiefs at Oakland Raiders

Best Bet: Raiders pick

All of the action seems to be on the Chiefs thus far as they opened as +2 underdogs but the line's been moved to a straight pick'em. Both of these teams look like they have work to do on defense as the Chiefs got absolutely shredded by the Steelers the week before their bye, while the Raiders continue to be completely unable to stop anyone week to week. It's very difficult to get a read on this Chiefs team as they've been all over the place thus far, but it's tough not to see the Raiders as small favorites at home here. Derek Carr continues to look great, so if the defense ever makes the jump to mediocre, the Raiders will have something brewing.

Atlanta Falcons at Seattle Seahawks

Best Bet: Over 45.5

Atlanta came away from Denver with a surprising blowout win and continues to be one of the pleasant surprises of the league through the early going. However, the defense still looks less than inspiring, ranking in the bottom half of the league against both the run and the pass. The offense is another story entirely, getting average-or-better play from almost everyone on the unit to produce what's thus far been a team nobody can really stop. The Seahawks do have a strong defense again, but we think the Falcons put up enough to get this over 45.5, and it's safe to assume Russell Wilson will do his part against the porous Falcons D.

Dallas Cowboys at Green Bay Packers

Best Bet: Packers -4

Aaron Rodgers at home is typically one of the safest bets in the NFL. Although the Packers failed to cover the opening number of -7.5 last week against the Giants, they easily could have won that game by double-digits. Rodgers hasn't been usual self thus far, completing just 56.1 percent of his passes and not really getting the ball downfield — his 6.3 yards per attempt would be a career-worst. A Cowboys side that's 25th against the pass could be the ticket to get Rodgers back on track, and the Cowboys should have trouble getting their strong rushing attack going against one of the league's premier run defenses thus far.

Indianapolis Colts at Houston Texans

Best Bet: Over 46

The Texans were completely stymied by the ferocious Vikings defense last week, and they have to be relieved to look at the schedule and see the awful Colts defense coming to town this week. That should be just the get-right spot they need, and look for Lamar Miller to finally find the end zone against the league's 31st-ranked rush defense. On the other side of the ball, Andrew Luck has managed to keep his sputtering offense somewhat ticking by continually hooking up with TY Hilton, and they should get just enough going to push this one over.

Monday, Oct. 17

NY Jets at Arizona Cardinals

Best Bet: Cardinals -7.5

The Jets continued to be completely helpless against opposing passing games last week as Ben Roethlisberger and the Steelers piled up four TDs and nearly 400 yards in a game that wasn't even competitive. The Cardinals at home and coming off of a bye will not be any easier for these guys, so expect another big game from Carson Palmer and Co. A ball-hawking defense is going to be ready to jump all over Ryan Fitzpatrick and his gifts, and this could one could get ugly in a hurry like a number of other Cardinals home games against bad teams in recent memory.