NFL Week 12: Betting Lines and Predictions for Every Game

All the picks in one place! The BookieSmash team breaks down every NFL game for Week 12, and offers the best bet for each game using our wide array of betting sites. Read on before placing your bets this week!


Minnesota Vikings at Detroit Lions

Best Bet: Over 41.5

It's a monster NFC North clash that few saw being this important before the season as the two teams with the best chance at winning the division meet in Detroit. Minnesota's defense is among the scariest out there, but they're hurting at the moment with Terence Newman likely sidelined and Harrison Smith not 100 percent. That should allow Detroit to move the ball better than expected through the air. Detroit's defense can't stop a nosebleed, though, so take over this very low total.

Washington Redskins at Dallas Cowboys

Best Bet: Redskins +7

There are a couple of very brutal matchups in this game for both defenses. The Redskins can't stop the run and Dallas has the best running game in football. On the other side of the ball, the Cowboys have a mediocre and injured pass defense and the Redskins bring in the sixth-ranked passing offense. The over is tempting but the total is a massive 52. If neither defense proves able to get consistent stops, the Redskins should stay within a score, though.

Pittsburgh Steelers at Indianapolis Colts

Best Bet: Colts +10

Everyone is lining up to fade the Colts, who will be without star QB Andrew Luck on Thursday. That's moved the line from an opener around +7.5 to +10. The Steelers defense is probably going to do some bad things to this mediocre defense, but it's still really tough to cover double digits on the road. Expect the rest of the Colts to rally here and play their best, enough to cover this huge numbers against Pittsburgh.


San Diego Chargers at Houston Texans

Best Bet: Chargers -1.5

The Texans return from Mexico City on a short week here after playing the Raiders on Monday night, a rough scheduling spot with the Chargers coming off of a bye. Brock Osweiler continues to struggle to move the Texans offense, and a surprisingly stout Chargers defense awaits here that's been excellent against the pass and solid against the run. As long as the Chargers can bottle up Lamar Miller here, they should be able to get Melvin Gordon and the TEs going against the Texans front seven.

Tennessee Titans at Chicago Bears

Best Bet: Bears +4.5

Jay Cutler may have played his last game in a Bears uniform after sustaining another injury, and backup Brian Hoyer is already done. That means it's down to Matt Barkley to pilot the Bears offense. Luckily, he gets a pretty soft landing against the Titans and their 26th-ranked pass defense. The key will be getting Jordan Howard and the running game going to take some pressure off Barkley and allow him to make some shorter throws. The Titans are dealing with some injuries that to key players Taylor Lewan and DeMarco Murray, so we'll take the Bears to keep things close at home.

Jacksonville Jaguars at Buffalo Bills

Best Bet: Over 44.5

The Bills come into the game still struggling to get healthy, with WR Robert Woods and RB LeSean McCoy either likely to sit out or be a bit limited. Luckily, one of the league's most elite running games will probably be able to move the ball as long as either McCoy or solid backup Mike Gillislee play. The Jags are terrible against the run, so if the Bills get things going early, Blake Bortles and Co. will be airing it out. That should result in points one way or another — either the Jags will score some TD passes or the Bills will get the weekly Bortles pick-six. Either way, we like the over.

Cincinnati Bengals at Baltimore Ravens

Best Bet: Ravens -4

An already disastrous Cincinnati season took a turn for the much worse in Week 11. Gio Bernard was lost for the year with a torn ACL and superstar WR AJ Green is out for the forseeable future with a strained hamstring. A very tough Baltimore defense has an easy assignment ahead, especially if CB Jimmy Smith suits up as expected. It looks like it will be almost impossible for the Bengals to move the rock, so the Ravens should get a cover at home even if the offense struggles as usual.

Arizona Cardinals at Atlanta Falcons

Best Bet: Falcons -4.5

Atlanta is coming off of its bye for a home date with a Cardinals team on the ropes. They'll have a tough time slowing down Cardinals RB David Johnson, who is just crushing week after week, but Carson Palmer looks like he's running on fumes at this point. Having a solid corner like Desmond Trufant helps greatly in the matchup with Larry Fitzgerald, and even a top-level Cardinals defense is unlikely to slow down the Falcons, who are just passing on everyone this year.

San Francisco 49ers at Miami Dolphins

Best Bet: 49ers +7.5

Teams are starting to load up the box against Jay Ajayi and the Dolphins as their running game continues to produce, and that strategy paid some dividends for the Rams last week as they were able to strangle the Dolphins until the secondary collapsed late. Expect the 49ers to copy that approach, and even their awful run defense should be able to put up resistance if they put enough guys near the line of scrimmage and make Ryan Tannehill beat them. The Dolphins are also hurting on the offensive line, and their passing game probably isn't good enough to pull away even against one of the league's bottom feeders.

LA Rams at New Orleans Saints

Best Bet: Saints -7

It was painfully obvious in Week 11 that the Rams are treating first overall pick Jared Goff with kiddie gloves, refusing to let him throw downfield or even try to get intermediate gains over the middle. That's not going to fly against the Saints, who will put up points in their offense-friendly dome as long as Drew Brees doesn't succumb to the turnover bug that bites him every now and then. The Saints roll at home here against the overwhelmed rookie.

NY Giants at Cleveland Browns

Best Bet: Giants -7

Another week, another disastrous performance from the Cleveland Browns. They were actually relatively competitive for a stretch before a late defensive touchdown sealed the cover for the Steelers in awful conditions in Cleveland. Thing is, that seems to be a weekly occurrence for this dismal team, and somewhat promising QB Cody Kessler is likely out here. Josh McCown has been a complete disaster, and we just can't trust this team at this point unless getting a considerably bigger number than +7.

Seattle Seahawks at Tampa Bay Bucs

Best Bet: Bucs +5.5

The Bucs are playing their best football of the year, coming off of a blowout home win against the Bears and then a shocking road win against the Chiefs. The same could probably be said of the Seahawks, though, making this a fun clash of teams pulling everything together. Losing exciting rookie RB CJ Prosise leaves the Seahawks down to one capable back in Thomas Rawls, which will hurt them on third downs when they need a pass catcher. Jameis Winston will have to avoid turnovers here, but Seattle's defense has picked up some injuries at the moment, so we like the Bucs to get a cover against the short-handed Hawks.

Carolina Panthers at Oakland Raiders

Best Bet: Panthers +3

Like the Texans, the Raiders were also dealt a bad hand by the schedule makers here. The Panthers are on 10 days of rest while the Raiders have to travel all the way back from Mexico City on a short week. That alone makes the Panthers worth a look, and getting a key number of +3 helps big time. One thing to keep an eye on here is the injury report, as star LB Luke Kuechly went down injured against the Saints on Thursday night. If he plays, it would be a major boost to the Panthers, but he's had concussion issues in the past so the team may be cautious.

KC Chiefs at Denver Broncos

Best Bet: Broncos -3

Injuries are also wrecking the Chiefs at the moment, and it really showed as they had a lot of trouble slowing down Jameis Winston and an average Tampa Bay offense. Marcus Peters, Dontari Poe, Derrick Johnson, and Dee Ford are all hurting. Ford in particular has been a major pass-rushing standout this year, and the team just can't afford to lose him and the ball-hawking Peters. The Broncos offense isn't very good, but they do have some skill position talent, and coming off a bye, we like them at home.

New England Patriots at NY Jets

Best Bet: Jets +8

Rob Gronkowski looks like he'll be sitting out again this week for the Pats. He's such a huge part of what the Patriots do on offense, and they didn't look much like the juggernaut that's been rolling over the league when the 49ers played with them step-for-step through the first half in Week 11. Without Gronk, the explosive plays just aren't there, and while Tom Brady was able to use his excellent pocket presence to evade the 49ers pass rushers by a whisker a number of times, the Jets have some of the most talented defensive linemen in the league. Unlike the 49ers, they'll get there a few times and keep the Pats offense just enough in check to cover.


Green Bay Packers at Philadelphia Eagles

Best Bet: Eagles -4

The one-dimensional Packers offense heads to Philly for a very rough assignment against the top-rated Eagles pass defense in what's almost a must-win game if the Packers want to have any chance of making a run at the division. Green Bay grabbed Christine Michael off the scrap heap to try to get the running game going, but the Seahawks castoff is unlikely to offer meaningful help. If Aaron Rodgers is struggling against some of the lesser defenses who have held him in check recently like the Colts and Titans, this isn't going to go well.

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